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  1. IDEAL Trial: Cooper, Bruce A., et al. “A randomized, controlled trial of early versus late initiation of dialysis.” New England Journal of Medicine (Early initiation no better than late initiation of dialysis.) Download
  2. EVOLVE Trial: Chertow, G. M., et al. “Effect of cinacalcet on cardiovascular disease in patients undergoing dialysis.” The New England journal of medicine 367.26 (2012): 2482-2494.(Cinacalcet doesn’t lower death or major CV event risks in patients undergoing dialysis.) Download
  3. ADAMEX Trial: Paniagua, Ramon, et al. “Effects of increased peritoneal clearances on mortality rates in peritoneal dialysis: ADEMEX, a prospective, randomized, controlled trial.” Journal of the American Society of Nephrology 13.5 (2002): 1307-1320.(Peritoneal dialysis version of HEMO no mortaility benefit) Download
  4. AURORA Trial: Fellström, Bengt, et al. “Effect of rosuvastatin on outcomes in chronic haemodialysis patients: baseline data from the AURORA study.” Kidney and Blood Pressure Research 30.5 (2007): 314-322. (No mortality benefit with ESRD patients with rosuvastatin) Download
  5. 4D Trial: Wanner, Christoph, et al. “Atorvastatin in patients with type 2 diabetes mellitus undergoing hemodialysis.” New England Journal of Medicine 353.3 (2005): 238-248. (No mortality benefit with ESRD patients with atorvastatin) Download
  6. SHARP Trial:

Nutrition in ESRD

  1. MICHAEL V ROCCO, JOHANNA T DWYER,. The effect of dialysis dose and membrane flux on nutritional parameters in hemodialysis patients: Results of the HEMO Study. Kidney International (2004) 65, 2321–2334.
  2. William F. Owen, Jr., Nancy L. Lew, Yan Liu, Edmund G. Lowrie, and J. Michael Lazarus. The Urea Reduction Ratio and Serum Albumin Concentration as Predictors of Mortality in Patients Undergoing Hemodialysis. N Engl J Med 1993; 329:1001-1006.
  3. Dr. Bengt Lindholm,. Serum Albumin as Predictor of Nutritional Status in Patients with ESRD. CJASN September 07, 2012 vol. 7 no. 9 1446-1453
  4. Sharon H Stall. Comparison of five body-composition methods in Peritoneal Dialysis patients. Am J Clin Nutr August 1996 vol. 64 no. 2 125-130.
  5. Fouque D, Kalantar-Zadeh K, Kopple J, et al: A proposed nomenclature and diagnostic criteria for protein-energy wasting in acute and chronic kidney disease. Kidney Int 2008; 73:391-398
  6. Cano NJ, Fouque D, Roth H, et al: Intradialytic parenteral nutrition does not improve survival in malnourished hemodialysis patients: A 2-year multicenter, prospective, randomized study. J Am Soc Nephrol 2007; 18:2583-2591.
  7. Let them eat during dialysis: an overlooked opportunity to improve outcomes in maintenance hemodialysis patients.J Ren Nutr. 2013 May ;23(3):157-63. doi:10.1053/j.jrn.2012.11.001. Epub 2013 Jan 10 .

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